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The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice. Conventionally, phage therapy relies on the use of naturally-occurring phages to infect and lyse bacteria at the site of infection. Biotechnological advances have further expanded the repertoire of potential phage therapeutics to include novel strategies using bioengineered phages and purified phage lytic proteins. Current research on the use of phages and their lytic proteins, specifically against multidrug-resistant bacterial infections, suggests phage therapy has the potential to be used as either an alternative or a supplement to antibiotic treatments. Antibacterial therapies, whether phage- or antibiotic-based, each have relative advantages and disadvantages; accordingly, many considerations must be taken into account when designing novel therapeutic approaches for preventing and treating bacterial infections. Although much is still unknown about the interactions between phage, bacteria, and human host, the time to take phage therapy seriously seems to be rapidly approaching.
Credit video :@biolution_net
#science #sciencemm #scientific #scientists #research #researchers #bacteriophage #visualscience #bacterial #medicalanimation #biology #biotechnology #biologist #videoftheday
Follow ➡@science.mm_.

The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice. Conventionally, phage therapy relies on the use of naturally-occurring phages to infect and lyse bacteria at the site of infection. Biotechnological advances have further expanded the repertoire of potential phage therapeutics to include novel strategies using bioengineered phages and purified phage lytic proteins. Current research on the use of phages and their lytic proteins, specifically against multidrug-resistant bacterial infections, suggests phage therapy has the potential to be used as either an alternative or a supplement to antibiotic treatments. Antibacterial therapies, whether phage- or antibiotic-based, each have relative advantages and disadvantages; accordingly, many considerations must be taken into account when designing novel therapeutic approaches for preventing and treating bacterial infections. Although much is still unknown about the interactions between phage, bacteria, and human host, the time to take phage therapy seriously seems to be rapidly approaching. Credit video :@biolution_net #science #sciencemm #scientific #scientists #research #researchers #bacteriophage #visualscience #bacterial #medicalanimation #biology #biotechnology #biologist #videoftheday Follow ➡@science.mm_ ...

Blood proteins such as fibrinogen, plasminogen and thrombin have essential functions in the maintenance of integral vasculature homeostatic processes involved in blood clotting. However, under pathological conditions a weakened blood–brain barrier (BBB) could allow extravasation of plasma proteins into parenchymal regions of the brain. A likely consequence of increased infiltration of proteins is the exacerbation of inflammatory responses mediated by the resident immune responding cells, microglia. At present, limited experimental evidence is available to characterize the links between abnormalities in properties of BBB, increased levels of plasma proteins in parenchyma, microglial inflammatory reactivity and neuronal degeneration and their contributions to chronic brain inflammation.

Alzheimer’s disease (AD) brains are characterized by considerable abnormalities and deficiencies in properties of BBB . Elevated levels of fibrinogen in brain parenchyma, due to extravasation of the glycoprotein through a weakened BBB, have also been reported in AD brain. Recent work has demonstrated fibrin deposition and damaged vasculature in three different transgenic animal models of AD . In these transgenic models, enhanced levels of fibrinogen exacerbated vascular damage whereas inhibition of fibrinogen attenuated neurovascular pathology. Interestingly, reduction of parenchymal fibrinogen was not associated with any efficacy for neuroprotection.
Credit pic : @ella_maru
#science #sciencemm #scientific #scientist #research #researcher #fibrinogen #brain #neurobiology #visualscience #scientificpic #biology #biotechnology
#medicalanimation 
Follow ➡@science.mm_.

Blood proteins such as fibrinogen, plasminogen and thrombin have essential functions in the maintenance of integral vasculature homeostatic processes involved in blood clotting. However, under pathological conditions a weakened blood–brain barrier (BBB) could allow extravasation of plasma proteins into parenchymal regions of the brain. A likely consequence of increased infiltration of proteins is the exacerbation of inflammatory responses mediated by the resident immune responding cells, microglia. At present, limited experimental evidence is available to characterize the links between abnormalities in properties of BBB, increased levels of plasma proteins in parenchyma, microglial inflammatory reactivity and neuronal degeneration and their contributions to chronic brain inflammation. Alzheimer’s disease (AD) brains are characterized by considerable abnormalities and deficiencies in properties of BBB . Elevated levels of fibrinogen in brain parenchyma, due to extravasation of the glycoprotein through a weakened BBB, have also been reported in AD brain. Recent work has demonstrated fibrin deposition and damaged vasculature in three different transgenic animal models of AD . In these transgenic models, enhanced levels of fibrinogen exacerbated vascular damage whereas inhibition of fibrinogen attenuated neurovascular pathology. Interestingly, reduction of parenchymal fibrinogen was not associated with any efficacy for neuroprotection. Credit pic : @ella_maru #science #sciencemm #scientific #scientist #research #researcher #fibrinogen #brain #neurobiology #visualscience #scientificpic #biology #biotechnology #medicalanimation Follow ➡@science.mm_ ...

I’ve lately spent a lot of time doing usability testing, so I figured I’d map out and share some methods and scenarios that enable you and help you run usability tests. 🙌🏻🔥 Based on a great article by Daniel Schwarz on UXtricks.design and with a beautiful illustration by Shiva Thallapalli via Dribbble.
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Share your experiences with usability testing! 🚀🦄
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#ux #ui #uiux #uxui #uxuidesign #uiuxdesign #uxdesign #uxdesign #userinterfacedesign #userexperiencedesign #uxdesigner #uidesigner #uxresearch #uxprocess #usability #usabilitytesting #usertesting #research #usabilitytests #uxdesignmastery #interfacedesign #appdesign #mobileappdesign #startup #tech #uxinspiration #uiinspiration #uxdesigning.

I’ve lately spent a lot of time doing usability testing, so I figured I’d map out and share some methods and scenarios that enable you and help you run usability tests. 🙌🏻🔥 Based on a great article by Daniel Schwarz on UXtricks.design and with a beautiful illustration by Shiva Thallapalli via Dribbble. • Share your experiences with usability testing! 🚀🦄 • • • #ux #ui #uiux #uxui #uxuidesign #uiuxdesign #uxdesign #uxdesign #userinterfacedesign #userexperiencedesign #uxdesigner #uidesigner #uxresearch #uxprocess #usability #usabilitytesting #usertesting #research #usabilitytests #uxdesignmastery #interfacedesign #appdesign #mobileappdesign #startup #tech #uxinspiration #uiinspiration #uxdesigning ...

Fossil Hunting.
When an animal or plant dies it is usually completely destroyed — either by another animal eating it or by decaying on the ground or in the water. But sometimes the animal is buried before it is destroyed. And when that happens and conditions are just right, the remains of the animal are preserved as fossils.
Earth is about 4.6 billion years old. The oldest known fossils are from rocks from about 3.5 billion years ago. At Shark Bay, Australia, you can see stromatolites.
Fossil collecting is the collection of fossils for scientific study, hobby, or profit. Professionals and amateurs alike collect fossils for their scientific value. A commercial trade in fossils has also long existed, with some of this being practised illegally.
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Credits :- @yorkshire.fossils
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#invention #science #geek #interesting #technology #worldofengineering #chemistry #talkwidtech #research #engineering #amazing #cliff #fossil #archaeology #geology #jurassic #stone #rock.

Fossil Hunting. When an animal or plant dies it is usually completely destroyed — either by another animal eating it or by decaying on the ground or in the water. But sometimes the animal is buried before it is destroyed. And when that happens and conditions are just right, the remains of the animal are preserved as fossils. Earth is about 4.6 billion years old. The oldest known fossils are from rocks from about 3.5 billion years ago. At Shark Bay, Australia, you can see stromatolites. Fossil collecting is the collection of fossils for scientific study, hobby, or profit. Professionals and amateurs alike collect fossils for their scientific value. A commercial trade in fossils has also long existed, with some of this being practised illegally. . Credits :- @yorkshire.fossils . . #invention #science #geek #interesting #technology #worldofengineering #chemistry #talkwidtech #research #engineering #amazing #cliff #fossil #archaeology #geology #jurassic #stone #rock ...

The words that we type into a Google search can reveal a lot about what's on our minds... and, they can even tell us about how we relate to birds! Cornell Lab researcher Justin Schuetz & Ali Johnston used #eBird, Google trends, and data from Merlin Bird ID to uncover a new way to think about how Americans relate to birds. Researchers found that Americans engaged with

The words that we type into a Google search can reveal a lot about what's on our minds... and, they can even tell us about how we relate to birds! Cornell Lab researcher Justin Schuetz & Ali Johnston used #eBird , Google trends, and data from Merlin Bird ID to uncover a new way to think about how Americans relate to birds. Researchers found that Americans engaged with "celebrity birds," such as owls, raptors, and sports mascots more often than "strangers," such as Lincoln's Sparrows.⠀ ~~⠀ Northern Pygmy-Owl | Glaucidium gnoma⠀ 📸: ©David Tønnessen / Macaulay Library, ML33886011⠀ ~~⠀ #NorthernPygmyOwl #Owl #science #communication #research #cornelllabofornithology #bird #birdstagram #birding #birdID #ornithology ...

The Orinoco Crocodile! ✅🐊 this species lives alongside Anacondas in the swamplands and river systems of Venezuela & Colombia! A pleasure to find one as they are Critically Endangered. They have been killed in the wild for their valuable hides for leather. Now ‘upstart’ wild breeding programmes are helping their populations recover, by looking after the eggs and hatchlings until they are bigger and more likely to survive to adulthood. 
#crocodile #wildlifeonearth #wildlife #naturelovers #nature #animals_in_world #animals #natureismetal #natureiscool #natureislit #species #orinoco #reptiles #expedition #venezuela #research #endangeredspecies #endangered #coolanimals #wildlife_seekers #llanos #llanosvenezolanos.

The Orinoco Crocodile! ✅🐊 this species lives alongside Anacondas in the swamplands and river systems of Venezuela & Colombia! A pleasure to find one as they are Critically Endangered. They have been killed in the wild for their valuable hides for leather. Now ‘upstart’ wild breeding programmes are helping their populations recover, by looking after the eggs and hatchlings until they are bigger and more likely to survive to adulthood. #crocodile #wildlifeonearth #wildlife #naturelovers #nature #animals_in_world #animals #natureismetal #natureiscool #natureislit #species #orinoco #reptiles #expedition #venezuela #research #endangeredspecies #endangered #coolanimals #wildlife_seekers #llanos #llanosvenezolanos ...

Most Recent

A team of prostate cancer researchers at St. Joe's new Urologic Cancer Centre for Research & Innovation (UCCRI) have been awarded over $575,000 from the Canadian Institutes of Health Research, for a 3 year study on castration-resistant prostate cancer. Learn more under

A team of prostate cancer researchers at St. Joe's new Urologic Cancer Centre for Research & Innovation (UCCRI) have been awarded over $575,000 from the Canadian Institutes of Health Research, for a 3 year study on castration-resistant prostate cancer. Learn more under "News" on our website: research.stjoes.ca . . . . . . . . #onHWS #urology #urologic #urological #cancer #prostate #prostatecancer #prostatecancerawareness #HamOnt #mcmasteru #research #healthscience #science #healthresearch #oncology #menshealth #innovation #discovery #genetics #molecularbiology #biology ...

1999⠀⠀
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CAR Director Robin Spence working with students from Cambridge university in his capacity as Senior Lecturer at Cambridge University Architecture Department (1975 to 2008)⠀⠀
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Students gingerly testing their bridges.⠀⠀
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#CAR_Cambridge #CAR_Timeline #Architecture #Consultancy ⁣#engineering #acoustics #construction #constructionindustry #socialscience #research #Cambridge #consultants #Bridge #buildingbridges ⠀⠀.

1999⠀⠀ ⠀⠀ CAR Director Robin Spence working with students from Cambridge university in his capacity as Senior Lecturer at Cambridge University Architecture Department (1975 to 2008)⠀⠀ ⠀⠀ Students gingerly testing their bridges.⠀⠀ ⠀⠀ #CAR_Cambridge #CAR_Timeline #Architecture #Consultancy#engineering #acoustics #construction #constructionindustry #socialscience #research #Cambridge #consultants #Bridge #buildingbridges ⠀⠀ ...

Children are the future of our nation, the more reason why we should invest in sustainable ventures that will ensure a better future for them. 
We at Bilaad want to aid you secure this future,  by providing sustainable housing solutions that will not only  guarantee a more secure future for them but deliver a better living and learning environment for them. 
Bilaad Realty our passion is people…
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#childrensday#kids#thefuture#youngones#bilaadkids#sustainablerealestates#estatesolutions #partnership#research #abujacity#Realestate#realestateabuja#realestateinvestor#realestateinvestment#bilaad
#sustainableconstruction#sustainability #luxury #lifestyle#premium #homes#urbanhouse#luxuryliving#realestatenigeria#realtor#designinspiration
#sustainability.

Children are the future of our nation, the more reason why we should invest in sustainable ventures that will ensure a better future for them. We at Bilaad want to aid you secure this future, by providing sustainable housing solutions that will not only guarantee a more secure future for them but deliver a better living and learning environment for them. Bilaad Realty our passion is people… _ _ _ #childrensday #kids #thefuture #youngones #bilaadkids #sustainablerealestates #estatesolutions #partnership #research #abujacity #Realestate #realestateabuja #realestateinvestor #realestateinvestment #bilaad #sustainableconstruction #sustainability #luxury #lifestyle #premium #homes #urbanhouse #luxuryliving #realestatenigeria #realtor #designinspiration #sustainability ...

Today, we remember, honor and thank those who have served our country and those who continue to serve..

Today, we remember, honor and thank those who have served our country and those who continue to serve. ...